Epi Fountain of Youth
“It's not that the old meds are getting weaker, drug developers say. It's as if the placebo effect is somehow getting stronger. The fact that an increasing number of medications are unable to beat sugar pills has thrown the industry into crisis.” US Food and Drug Administration
PLACEBO EFFECT = EPIGENETICS = Changing the physiology of my body through my perceptions
According to the National Center for Biotechnology Information, U.S. National Library of Medicine, placebo effects were found when comparing the results of patients who had had keen surgery and those who had had sham keen surgery as follows. No difference was found for debridement versus arthroscopic lavage of the knee versus placebo. They stated “The fact that some of the “placebo” patients fared better than those who had undergone surgery cannot be conclusively explained. The assumption is that the numerous signal substances that are produced naturally in the body, which are epigenetically influenced by the conscious mind as well as by emotions, may exert a substantial influence on the physiology of the healing process (see adjacent video, read study in references).
"I think, therefore I am", René Descartes, father of modern western philosophy 1596 -1650
A study recently published in PLOS one (Catechol-O-Methyltransferase val158met Polymorphism Predicts Placebo Effect in Irritable Bowel Syndrome) purports to have found a gene variant that correlates strongly with a placebo response in irritable bowel syndrome (IBS). (see study in references)
Harvard University, 2007, Mind-set Matters: Exercise and the Placebo Effect— “In this study testing whether the relationship between exercise and health is moderated by one’s mindset, 84 female room attendants working in seven different hotels were measured on physiological health variables affected by exercise. Those in the informed condition were told that the work they do (cleaning hotel rooms) is good exercise and satisfies the Surgeon General’s recommendations for an active lifestyle. Examples of how their work was exercise were provided. Subjects in the control group were not given this information. Although actual behavior did not change, 4 weeks after the intervention, the informed group perceived themselves to be getting significantly more exercise than before. As a result, compared with the control group, they showed a decrease in weight, blood pressure, body fat, waist-to-hip ratio, and body mass index. These results support the hypothesis that exercise affects health in part or in whole via the placebo effect.” (see adjacent video, read study in references)
Dr. Moseley Placebo surgery video 5:33 sec
CBS video 00:43 sec
The American College of Sports Medicine 1972 –“ Fifteen male varsity athletes were informed that some of them would be selected to receive an anabolic steroid (Dianabol). Instead, six selected subjects were given placebo pills. Taking the placebo apparently supplied the psychological inducement to increase strength gains above and beyond reasonable progression. Greater training gains were made during the placebo period in three out of four weight lifting exercises. The gains were statistically significant when comparing the two regression lines for the pre-placebo and placebo periods.”
“There is evidence supporting the idea that the placebo effect plays a role in occasioning the psychological benefits associated with exercise.” Dr. Ellen Langer, Harvard University
Once again, that premises “changing the physiology of your body through your perceptions”. In the studies mentioned I noticed one common thread amongst the placebo keen surgery, 42 female room attendants, and the six male varsity athletes that changed the physiology of their bodies was that they truly believed the information given to them. I thought to myself, if the placebo effect has had this type of positive impacted on these studies and others I had read base on the premise of belief, then regardless if I had years of scientific or metaphysical proof or not of my concepts as long as I truly believed in them, the chances of success in changing the physiology of my body through my perceptions” increase.
Dr. Irving Kirsch 60 Minutes video 1:15 sec
CBS video Dr. Ellen Langer 0:43 sec
While most people are familiar with the placebo effect many are not familiar with the nocebo effect. The nocebo is basically the opposite of the placebo. For the most part while the placebo has as a positive effect the nocebo has a negative effect. Put simply, it is the phenomenon in which inert substances or mere suggestions of substances actually bring about negative effects in a patient or research participant. For some, being informed of a pill or procedure’s potential side effects is enough to bring on real-life side effect symptoms.
"If the brain expects that a treatment will work, it sends healing chemicals into the bloodstream, which facilitates that. And the opposite is equally true and equally powerful: When the brain expects that a therapy will not work, it doesn't. It's called the 'nocebo' effect." - Dr. Bruce Lipton
Like many people I was lead to believe that the placebo effect was some type of scam or fraud and that there were no benefits and in fact may have adverse effects. In many case there are those in the scientific and medical community that still share this perspective. That was until I got out of my societal engineering of this mental constructs and discovered the following.
Voice of Dr. Bruce Lipton video 3:41 sec